Methods in enzymology. Volume five hundred and forty two,...

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Methods in enzymology. Volume five...

Methods in enzymology. Volume five hundred and forty two, Conceptual background and bioenergetic/mitochondrial aspects of oncometabolism

Name: Methods in enzymology. Volume five hundred and forty two, Conceptual background and bioenergetic/mitochondrial aspects of oncometabolism
ISBN: 9780124166578

Lorenzo Galluzzi, Guido Kroemer, Woo Suk Ahn

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Volume 542 of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This new volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as ''yet another'' general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation.

Continues the legacy of this premier serial with quality chapters authored by leaders in the field
Covers research methods in biomineralization science
Provides theoretical overview on metabolic alterations of cancer cells, and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo

Categorías:

Medicine

Año:

2014

Edición:

Editorial:

Academic Press

Idioma:

english

Páginas:

565

ISBN 10: